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Prof Glen Cottrell:
Professor (Emeritus)


Research Overview:
Prof Glen Cottrell

Prof Glen Cottrell
Biomolecular Sciences Building
University of St Andrews
North Haugh
St Andrews
KY16 9ST
Fife
UK

tel: 01334 463572
fax: 01334 462595
room:
email: gac@st-andrews.ac.uk

Related Content:



Neuroscience and Cell Signalling
School of Biology
Institute of Behavioural and Neural Sciences
IBANS Animal Cognition

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Novel ligand-gated ion channels in nerve cells.


Nerve cells communicate by releasing chemical messengers, often referred to as neurotransmitters. Some neurotransmitters exert fast effects (via ligand-gated ion channels) others slow effects (via enzyme coupled receptors). We have recently discovered fast actions of two transmitters hithertoo only thought to produce slow effects: a neuropeptide, FMRFamide, and dopamine. The channels directly gated by these substances are being studied in detail. The peptide gated channel (now cloned) is unique in showing a high selectivity for Na ions and also in being antagonised by another endogenous, related, peptide.

 


5 (of 15 published available) for gac (source: University of St Andrews PURE)
Please click title of any item for full details

Fast silencing reveals a lost role for reciprocal inhibition in locomotion Peter Robert Moult, Glen Alfred Cottrell, Wenchang Li
Neuron 2013 vol.77 pp.129-140
Green laser light (532nm) activates a chloride current in the C1 neuron of Helix aspersa P J Reece, Kishan Dholakia, R C Thomas, Glen Alfred Cottrell
Neuroscience Letters 2008 vol.433 pp.265-269
Green light activates some and inhibits other neurons of snail ganglia P J Reece, K Dholakia, Glen Alfred Cottrell
2007
Domain near TM1 influences agonist and antagonist responses of peptide-gated Na(+) channels. Glen Alfred Cottrell
Pflügers Archiv: European Journal of Physiology 2005 vol.450 pp.168-177
Activity modes and modulation of the peptide-gated Na(+) channel of Helix neurones KA Green, Glen Alfred Cottrell
Pflügers Archiv: European Journal of Physiology 2002 vol.443 pp.813-821