Prof Glen Cottrell:
Prof Glen Cottrell
Biomolecular Sciences Building
University of St Andrews
tel: 01334 463572
fax: 01334 462595
Neuroscience and Cell Signalling
School of Biology
Institute of Behavioural and Neural Sciences
IBANS Animal Cognition
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Novel ligand-gated ion channels in nerve cells.
Nerve cells communicate by releasing chemical messengers, often referred to as neurotransmitters. Some neurotransmitters exert fast effects (via ligand-gated ion channels) others slow effects (via enzyme coupled receptors). We have recently discovered fast actions of two transmitters hithertoo only thought to produce slow effects: a neuropeptide, FMRFamide, and dopamine. The channels directly gated by these substances are being studied in detail. The peptide gated channel (now cloned) is unique in showing a high selectivity for Na ions and also in being antagonised by another endogenous, related, peptide.
Data could not be retrieved from PURE at this time. (research-outputs/persons)