Dr Gareth Miles:

Research Overview:
Dr Gareth Miles

Dr Gareth Miles
Bute Building
University of St Andrews
St Andrews
KY16 9TS

tel: 01334 463281
fax: 01334 463600
room: B13

Related Content:

NCM lab

School of Psychology and Neuroscience
Institute of Behavioural and Neural Sciences
IBANS Animal Cognition
Neural Control of Movement

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The primary goal of the research in my laboratory is to provide a better understanding of the neural control of movement with a focus on motor systems of the brainstem and spinal cord. A detailed knowledge of the normal physiology of these systems is required to enable us to understand and ultimately treat neurodegenerative diseases and injuries which can afflict them. My lab's interests extend from the level of ion channels on individual neurons up to entire neuronal networks involved in  motor behaviours. We study the physiology and anatomy of motor systems both in their normal 'healthy' state and when they are affected by conditions such as Motor Neuron Disease (MND).

Lab website:


5 (of 33 published available) for gbm4 (source: University of St Andrews PURE)
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Photostimulation for in vitro optogenetics with high power blue organic light-emitting diodes Andrew Morton, Caroline Murawski, Changmin Keum, Gareth Brian Miles, Javier Ananda Tello, Malte Christian Gather
Advanced Biosystems 2019 vol.3
Pitx2 cholinergic interneurons are the source of C bouton synapses on brainstem motor neurons Ismini Rozani, Georgia Tsapara, S. James Deaville, Gareth Brian Miles, Laskaro Zagoraiou
Scientific Reports 2019 vol.9
C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity Bhuvaneish Thangaraj Selvaraj , Matthew Livesey , Chen Zhao , Jenna Gregory , Owain James, Elaine Cleary, Angus Gane, Emma Perkins, Owen Dando, Simon Lillico, Younbok Lee, Agnes Nishimura, Urjana Poreci, Sai Thankamony, Meryll Pray, Navneet Vasistha, Dario Magnani, Shyamanga Borooah, Karen Burr, David Story, Alexander McCampbell, Christopher Shaw, Peter Kind, Tim Aitman, Bruce Whitelaw, Ian Wilmut, Colin Smith, Gareth Brian Miles, Giles Hardingham, David Wyllie, Siddharthan Chandran
Nature Communications vol.9
Modulation of spinal motor networks by astrocyte-derivsed adenosine is dependent on D1-like dopamine receptor signalling David Acton, Matthew James Broadhead, Gareth Brian Miles
Journal of Neurophysiology 2018 vol.120 pp.998-1009
Differential regulation of NMDA receptors by D-serine and glycine in mammalian spinal locomotor networks David Acton, Gareth Brian Miles
Journal of Neurophysiology 2017 vol.117 pp.1877-1893